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| 1800 |
| | | Toussaint L'Ouverture emerges as the leader of Saint-Domingue, ruling without French colonial control | |
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| 1801 |
| | | The Act of Union comes into effect, linking Ireland with Britain to form the United Kingdom | |
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| 1801 |
| | | The US House of Representatives votes for Jefferson as president, after a dead heat between him and Burr in the Electoral College | |
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| 1801 |
| | | Toussaint L'Ouverture invades the neighbouring Spanish colony of Santo Domingo, and becomes ruler of of the whole island of Hispaniola | |
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| 1801 |
| | | British prime minister William Pitt resigns when George III vetoes Catholic emancipation, but is recalled three years later | |
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| 1802 |
| | | The Constitution of the Year XII (the twelfth year of the French Revolutionary Calendar) makes Napoleon First Consul for life | |
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| 1803 |
| | | The Frankfurt banker Mayer Amschel Rothschild lends 20 million francs to the Danish government | |
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| 1803 |
| | | In Marbury v. Madison, a landmark example of judicial review, the US Supreme Court declares an act of Congress to be unconstitutional | |
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| 1803 |
| | | In the Louisiana Purchase, Jefferson buys from Napoleon nearly a million square miles at a knock-down price, doubling the size of the USA | |
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| 1805 |
| | | Lord Castlereagh becomes secretary of state for war in William Pitt's government | |
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